Original Articles Open access

Upper airway and eye involvement in polyurethane shoe sole production workers

[Sintomi delle vie aeree superiori e delle congiuntive nei lavoratori addetti alla produzione di suole in poliuretano per calzature*

Authors

Published
3 April 2025
Section
Original Articles
DOI
10.4081/gimle.657
Pages
89-95

Abstract

Objectives: This cross-sectional study was aimed to investigate the prevalence of work-related upper and lower airway and eye symptoms in 118 workers in polyurethane shoe soles (PSS) production. Methods: Workplace monitoring of methylene diphenyl disocyanate (MDI) and solvents was performed. Subjects completed a study-specific questionnaire and underwent anterior rhinoscopy, skin prick tests for common aeroallergens, spirometry, nasal peak inspiratory (NPIF) and expiratory flow (NPEF).
Results: MDI and solvent levels were below threshold limit value-time-weighted average (TLW-TWA) except for two measures of dichloromethane and tetrachloroethylene, respectively, and in one measure of acetonitrile, which were higher then TLW-TWA. In exposed workers the prevalence of cough (p<0.05) and nasal congestion at rhinoscopy (p= 0.05) was more frequent than in non-exposed workers. Occupational exposure (OR 4.5, 95% CI 1.2-16.5) and a low FEV, (OR 2.6, 95% CI 1.1-6.3) were significant predictors of cough. Conclusions: In workers exposed to low levels of MDI and solvents in polyurethane shoe sole production there was a high prevalence of cough and nasal congestion. An improvement in the exhaust ventilation system and other preventive measures were needed.

References

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