ATTI 80° CONGRESSO NAZIONALE SIML Open access

[Health and work from a gender perspective]

Salute e lavoro in un’ottica di genere

Authors

Published
3 March 2025
Section
ATTI 80° CONGRESSO NAZIONALE SIML
DOI
10.4081/gimle.633
Pages
203-210

Abstract

A literature review was performed to highlight which work-related diseases express sex/gender differences in health outcomes and focus the main limits of studies in this field. The research, carried out on PubMed by specific search string, identified 4828 articles (1997-2017 period) of which 381 are eligible for review (4-22%, depending on the disease). Among them, 68% reported sex/gender differences in health outcomes, which in most cases appear to be due to different exposure and/or work segregation rather than to biological differences. However, few studies place this assessment among the research goals and results are almost never discussed and hypothesis are seldom formulated about any observed differences. It seems necessary to use research methodologies and study design that can detect and explain the described complexity and useful in defining appropriate preventive strategies.

References

  1. 1) Putting gender on the agenda. Nature 2010; 465(7299): 665. DOI: https://doi.org/10.1038/465665a
  2. 2) Schiebinger L. Scientific research must take gender into account. Nature 2014; 507(7490): 9. DOI: https://doi.org/10.1038/507009a
  3. 3) Mattioli S, Zanardi F, Baldasseroni A, Schaafsma F, Cooke R MT, Mancini G, Fierro M, Santangelo C, Farioli A, Fucksia S, CurtiS, Violante FS, Verbeek J. Search strings for the study of putative occupational determinants of disease. Occup Environ Med 2010; 67: 436-443. DOI: https://doi.org/10.1136/oem.2008.044727
  4. 4) Baldi I, Lebailly P, Mohammed-Brahim B, Letenneur L, Dartigues JF, Brochard P. Neurodegenerative diseases and exposure to pesticides in the elderly. Am J Epidemiol 2003; 157: 409-414. DOI: https://doi.org/10.1093/aje/kwf216
  5. 5) Firestone JA, Lundin JI, Powers KM, Smith-Weller T, Franklin GM, Swanson PD, Longstreth Jr WT, Checkoway H. Occupational factors and risk of Parkinson's disease: a population-based case-control study. Am J Ind Med 2010; 53: 217-223. DOI: https://doi.org/10.1002/ajim.20788
  6. 6) Heyer NJ, Echeverria D, Bittner Jr AC, Farin FM, Garabedian CC, Woods JS. Chronic low-level mercury exposure, BDNF polymorphism, and associations with self-reported symptoms and mood. Toxicol Sciences 2004; 8: 354-363. DOI: https://doi.org/10.1093/toxsci/kfh220
  7. 7) Heyer NJ, Echeverria D, Martin MD, Farin FM, Woods JS. Cathecol O-Methyltransferase (COMT) VAL158METfunctionalpolymorphism, dental mercury exposure, and self-reported symptoms and mood. J Toxicol Environ Health A 2009; 72(9): 599-609. DOI: https://doi.org/10.1080/15287390802706405
  8. 8) Echeverria D, Woods JS, Heyer NJ, Martin MD, Rohlman DS, Farin FM, Li T. The association between serotonin transporter gene promotor polymorphism (S-HTTLPR) and elemental mercury exposure on mood and behavior in humans. J Toxicol Environ Health A 2010; 73(15): 1003-1020. DOI: https://doi.org/10.1080/15287390903566591
  9. 9) Andersson E, Person B, Bryngelsson I-L, Magnuson A, Toren K, Wingren G, Westberg H. Cohort mortality study of Swedish pulp and paper mill workers -non malignant diseases. Scand J Work Environ Health 2007; 33(6): 470-478. DOI: https://doi.org/10.5271/sjweh.1173
  10. 10) Ilychova SA, Zaridze DG. Cancer mortality among female and male workers occupationally exposed to inorganic lead in the printing industry. Occup Environ Med 2012; 69: 87-92. DOI: https://doi.org/10.1136/oem.2011.065201
  11. 11) Manuwald U, Garrido MV, Berger J, Manza A, Baur X. Mortality study of chemical workers exposed to dioxins: follow-up 23 years after chemical plant closure. Occup Environ Med 2012; 69: 636-642. DOI: https://doi.org/10.1136/oemed-2012-100682
  12. 12) Costello S, Picciotto S, Rehkopf DH, Eisen EA. Social disparities in heart disease risk and survivor bias among autoworkers: an examination based on survival models and g-estimation. Occup Environ Med 2015; 72: 138-144. DOI: https://doi.org/10.1136/oemed-2014-102168
  13. 13) Loh C-H, ShihT-S, Liou S-H, Lin Y-C, Hsieh A-T, Chen C-Y, Liao G-D. Occup Environ Med 2003; 60:e7. DOI: https://doi.org/10.1136/oem.60.9.e7
  14. 14) Chen H-I, Liou S-H, Hsieh A-T, ShihT-S, Sun C-W, Wu T-N, Chang H-Y, Loh C-H. J Occup Health 2007; 49: 285-29. DOI: https://doi.org/10.1539/joh.49.285
  15. 15) Oishi H, Nomiyama H, Nomiyama K, Tomokuni K. Comparison between males and females with respect to the porphyrin metabolic disorders found in workers occupationally exposed to lead. Int Arch Occup Environ Health 1996; 68: 298-304. DOI: https://doi.org/10.1007/BF00409414
  16. 16) Diepgen TL, Coenraads PJ, Williams HC, Strachan DP. Inflammatory skin diseases II: Contact dermatitis. Boca Raton, FL:CRC Press, Inc., 1997; 145-161.
  17. 17) Schwensen JE, Friis UF, Menné T, Johansen JD. One thousand cases of severe occupational contact dermatitis. Contact Dermatitis 2013;68(5): 259-68. DOI: https://doi.org/10.1111/cod.12045
  18. 18) Bangsgaard N, Thyssen JP, Menné T, Andersen KE, Mortz CG, Paulsen E, Sommerlund M, Veien NK, Laurberg G, Kaaber K, Thormann J, Andersen BL, Danielsen A, Avnstorp C, Kristensen B, Kristensen O, Vissing S, Nielsen NH, Johansen JD. Contact allergy to epoxy resin: risk occupations and consequences. Contact Dermatitis 2012; 67(2): 73-7. DOI: https://doi.org/10.1111/j.1600-0536.2012.02072.x
  19. 19) Bensefa-Colas L, Telle-Lamberton M, Faye S, Bourrain JL, Crépy MN, Lasfargues G, Choudat D; RNV3P members, Momas I. Occupational contact urticaria: lessons from the French National Network for Occupational Disease Vigilance and Prevention (RNV3P). Br J Dermatol 2015; 173(6): 1453-61. DOI: https://doi.org/10.1111/bjd.14050
  20. 20) Taillé C, Raherison C, Sobaszek A, Thumerelle C, Prudhomme A, Biron E, Nocent C, Tillie-Leblond I. Features of asthma in women: what is the relationship with hormonal status? Rev Mal Respir 2014; 31(6): 469-77. DOI: https://doi.org/10.1016/j.rmr.2014.02.005
  21. 21) Dodd KE, Mazurek JM. Asthma Among Employed Adults, by Industry and Occupation - 21 States, 2013. MMWR Morb Mortal Wkly Rep 2016; 65(47): 1325-1331. DOI: https://doi.org/10.15585/mmwr.mm6547a1
  22. 22) Dumas O, Siroux V, Luu F, Nadif R, Zock JP, Kauffmann F, Le Moual N. Cleaning and asthma characteristics in women. Am J Ind Med 2014; 57(3): 303-11. DOI: https://doi.org/10.1002/ajim.22244
  23. 23) Fell AK, Abrahamsen R, Henneberger PK, Svendsen MV, Andersson E, Torén K, Kongerud J. Breath-taking jobs: a case-control study of respiratory work disability by occupation in Norway. Occup Environ Med 2016; 73(9): 600-606. DOI: https://doi.org/10.1136/oemed-2015-103488
  24. 24) Gaxiola M, Buendía-Roldán I, Mejía M, Carrillo G, Estrada A, Navarro MC, Rojas-Serrano J, Selman M. Morphologic diversity of chronic pigeon breeder's disease: clinical features and survival. Respir Med 2011; 105(4): 608-614. DOI: https://doi.org/10.1016/j.rmed.2010.11.026
  25. 25) Morozova OA. Gender differences in death causes and survival rate of silicosis patients]. Med Tr Prom Ekol. 2012; 9: 32-36.
  26. 26) Ji J, Hemminki K. Occupation and upper aerodigestive tract cancers: a follow-up study in Sweden. Occup Environ Med 2005; 47(8): 78527) Travier N, Gridley G, De Roos AJ, Plato N, Moradi T, Boffetta P. Cancer incidence of dry cleaning, laundry and ironing workers in Sweden. Scand J Work Environ Health 2002; 28(5): 341-348. DOI: https://doi.org/10.5271/sjweh.684
  27. 28) Aronson KJ, Howe GR, Carpenter M, Fair ME. Surveillance of potential associations between occupations and causes of death in Canada, 1965-91. Occup Environ Med 1999; 56(4): 265-269. DOI: https://doi.org/10.1136/oem.56.4.265
  28. 29) Wang X, Lin S, Yu I, Qiu H, Lan Y, Yano E. Cause-specific mortality in a Chinese chrysotile textile worker cohort. Cancer Sci 2013; 104(2): 245-249.
  29. 30) Kaerlev L, Hansen J, Hansen HL, Nielsen PS. Cancer incidence among Danish seafarers: a population based cohort study. Occup Environ Med 2005; 62(11): 761-765. DOI: https://doi.org/10.1136/oem.2005.020818
  30. 31) Innos K, Rahu M, Rahu K, Lang I, Leon DA. Wood dust exposure and cancer incidence: a retrospective cohort study of furniture workers in Estonia. Am J Ind Med 2000; 37(5): 501-511. DOI: https://doi.org/10.1002/(SICI)1097-0274(200005)37:5<501::AID-AJIM6>3.0.CO;2-T
  31. 32) t'Mannetje A, Kogevinas M, Luce D, Demers PA, Bégin D, BolmAudorff U, Comba P, Gérin M, Hardell L, Hayes RB, Leclerc A, Magnani C, Merler E, Tobías A, Boffetta P. Sinonasal cancer, occupation, and tobacco smoking in European women and men. Am J Ind Med 1999; 36(1): 101-107. DOI: https://doi.org/10.1002/(SICI)1097-0274(199907)36:1<101::AID-AJIM14>3.3.CO;2-1
  32. 33) Guo H, Huang K, Zhang X, Zhang W, Guan L, Kuang D, Deng Q, Deng H, Zhang X, He M, Christiani D, Wu T. Women are more susceptible than men to oxidative stress and chromosome damage caused by polycyclic aromatic hydrocarbons exposure. Environ Mol Mutagen 2014; 55(6): 472-8. DOI: https://doi.org/10.1002/em.21866
  33. 34) Pira E, Romano C, Violante FS, Farioli A, Spatari G, La Vecchia C, Boffetta P. Updated mortality study of a cohort of asbestos textile workers. Cancer Med 2016; 5(9): 2623-2628. DOI: https://doi.org/10.1002/cam4.824
  34. 35) Lewis RJ, Schnatter AR, Katz AM, Thompson FS, Murray N, Jorgensen G, Thériault G. Updated mortality among diverse operating segments of a petroleum company. Occup Environ Med 2000; 57(9): 595-604. DOI: https://doi.org/10.1136/oem.57.9.595
  35. 36) Richardson DB, Wing S, Keil A, Wolf S. Mortality among workers at Oak Ridge National Laboratory. Am J Ind Med 2013; 56(7): 725-732. DOI: https://doi.org/10.1002/ajim.22164
  36. 37) Wang X, Lin S, Yu I, Qiu H, Lan Y, Yano E. Cause-specific mortality in a Chinese chrysotile textile worker cohort. Cancer Sci 2013; 104(2): 245-249. DOI: https://doi.org/10.1111/cas.12060
  37. 38) Laakkonen A, Kyyrönen P, Kauppinen T, Pukkala EI. Occupational exposure to eight organic dusts and respiratory cancer among Finns. Occup Environ Med 2006; 63(11): 726-733. DOI: https://doi.org/10.1136/oem.2005.025825
  38. 39) Bosilkovski M, Krteva L, Dimzova M, Kondova I. Brucellosis in 418 patients from the Balkan Peninsula: exposure-related differences in clinical manifestations, laboratory test results, and therapy outcome. Int J Infect Diseases 2007; 11: 342-347. DOI: https://doi.org/10.1016/j.ijid.2006.10.002
  39. 40) Sayin-Kutlu S, Kutlu M, Ergonul O, Akalin S, Guven T, Demiroglu Y.Z, Acicbe O, Akova M. Occupational Infectious Diseases Study Group 1. Laboratory-acquired brucellosis in Turkey. J Hosp Infect 2012; 80: 326-330. DOI: https://doi.org/10.1016/j.jhin.2011.12.020
  40. 81) Herin F, Vézina M, Thaon I, Soulat JM, Paris C; ESTE V group. Predictive risk factors for chronic regional and multisite musculoskeletal pain: a 5-year prospective study in a working population. Pain 2014; 155(5): 937-943. DOI: https://doi.org/10.1016/j.pain.2014.01.033
  41. 82) Hooftman WE, van der Beek AJ, Bongers PM, van Mechelen W. Is there a gender difference in the effect of work-related physical and psychosocial risk factors on musculoskeletal symptoms and related sickness absence? Scand J Work Environ Health 2009; 35(2):85-95. 83) Silverstein B, Fan ZJ, Smith CK, Bao S, Howard N, Spielholz P, Bonauto D, Viikari-Juntura E. Gender adjustment or stratification in discerning upper extremity musculoskeletal disorder risk? Scand J Work Environ Health 2009; 35(2): 113-126. DOI: https://doi.org/10.5271/sjweh.1309
  42. 84) Roquelaure Y, Ha C, Leclerc A, Touranchet A, Sauteron M, Melchior M, Imbernon E, Goldberg M. Epidemiologic surveillance of upperextremity musculoskeletal disorders in the working population. Arthritis Rheum 2006; 55(5): 765-778.
  43. 85) Heilskov-Hansen T, Mikkelsen S, Svendsen SW, Thygesen LC, Hansson GA, Thomsen JF. Exposure-response relationships between movements and postures of the wrist and carpal tunnel syndrome among male and female house painters: a retrospective cohort study. Occup Environ Med 2016; 73(6): 401-408. DOI: https://doi.org/10.1136/oemed-2015-103298
  44. 86) Jenkins PJ, Srikantharajah D, Duckworth AD, Watts AC, McEachan JE. Carpal tunnel syndrome: the association with occupation at a population level. J Hand Surg Eur Vol 2013; 38(1): 67-72. DOI: https://doi.org/10.1177/1753193412455790
  45. 87) Mattioli S, Baldasseroni A, CurtiS, Cooke RM, Mandes A, Zanardi F, Farioli A, Buiatti E, Campo G, Violante FS. Incidence rates of surgically treated idiopathic carpal tunnel syndrome in blue- and whitecollar workers and housewives in Tuscany, Italy. Occup Environ Med 2009; 66(5): 299-304. DOI: https://doi.org/10.1136/oem.2008.040212
  46. 88) Bongers FJ, Schellevis FG, van den Bosch WJ, van der Zee J. Carpal tunnel syndrome in general practice (1987 and 2001): incidence and the role of occupational and non-occupational factors. Br J Gen Pract 2007; 57(534): 36-39.
  47. 89) Roquelaure Y, Ha C, Leclerc A, Touranchet A, Sauteron M, Melchior M, Imbernon E, Goldberg M Epidemiologic surveillance of upperextremity musculoskeletal disorders in the working population. Arthritis Rheum 2006; 55(5): 765-778. DOI: https://doi.org/10.1002/art.22222
  48. 90) Abbas J, Hamoud K, May H, Peled N, Sarig R, Stein D, Alperovitch-Najemson D, Hershkovitz I. Socioeconomic and physical characteristics of individuals with degenerative lumbar spinal stenosis. Spine (PhilaPa 1976) 2013; 38(9): E554-61. DOI: https://doi.org/10.1097/BRS.0b013e31828a2846
  49. 91) Leino-Arjas P, Kaila-Kangas L, Kauppinen T, Notkola V, Keskimäki I, Mutanen P. Occupational exposures and inpatient hospital care for lumbar intervertebral disc disorders among Finns. Am J Ind Med 2004; 46(5): 513-520. DOI: https://doi.org/10.1002/ajim.20084
  50. 92) Somville FJ, De Gucht V, Maes S. The impact of occupational hazards and traumatic events among Belgian emergency physicians. Scand J Trauma Resusc Emerg Med 2016; 27: 24-59. DOI: https://doi.org/10.1186/s13049-016-0249-9
  51. 93) Kopacz MS, Currier JM, Drescher KD, Pigeon WR. Suicidal behavior and spiritual functioning in a sample of Veterans diagnosed with PTSD. J Inj Violence Res 2016; 8: 6-14.
  52. 94) Rybojad B, Aftyka A, Baran M, Rzonca P. Risk Factors for Posttraumatic Stress Disorder in Polish Paramedics: A Pilot Study. J Emerg Med 2016; 50(2): 270-276. DOI: https://doi.org/10.1016/j.jemermed.2015.06.030
  53. 95) Maguen S, Luxton DD, Skopp NA, Madden E. Gender differences in traumatic experiences and mental health in active duty soldiers redeployed from Iraq and Afghanistan. J Psychiatr Res 2012; 46(3): 311-316 96) Fichera GP, Neri L, Musti M, Coggiola M, Russignaga D, Costa G. Progress of PTSD symptoms following workplace robbery: gender and age differences in a sample of bank employees. G Ital Med Lav Ergon. 2011; 33(3 Suppl): 351-354. DOI: https://doi.org/10.1016/j.jpsychires.2011.11.007
  54. 97) Bowler RM, Han H, Gocheva V, Nakagawa S, Alper H, DiGrande L, Cone JE. Gender differences in probable posttraumatic stress disorder among police responders to the 2001 World Trade Center terrorist attack. Am J Ind Med. 2010; 53(12): 1186-1196. DOI: https://doi.org/10.1002/ajim.20876
  55. 98) Porto GG, Carneiro SC, Vasconcelos BC, Nascimento MM, Leal JL. Burnout syndrome in oral and maxillofacial surgeons: a critical analysis. Int J Oral Maxillo fac Surg 2014; 43(7): 894-899. DOI: https://doi.org/10.1016/j.ijom.2013.10.025
  56. 99) Amigo I, Asensio E, Menéndez I, Redondo S, Ledesma JA. Working in direct contact with the public as a predictor of burnout in the banking sector. Psicothema 2014; 26(2): 222-226. DOI: https://doi.org/10.7334/psicothema2013.282
  57. 100) Palazzo L dos S, Carlotto MS, Aerts DR. Burnout Syndrome: population-based study on public servants. Rev Saude Publica 2012; 46(6): 1066-1073. DOI: https://doi.org/10.1590/S0034-89102013005000004
  58. 101) Pavlakis A, Raftopoulos V, Theodorou M. Burnout syndrome in Cypriot physiotherapists: a national survey. BMC Health Serv Res 2010; 10:63. DOI: https://doi.org/10.1186/1472-6963-10-63
  59. 102) Vercambre MN, Brosselin P, Gilbert F, Nerrière E, Kovess-Masféty V. Individual and contextual covariates of burnout: a cross-sectional nationwide study of French teachers. BMC Public Health 2009; 9: 333. DOI: https://doi.org/10.1186/1471-2458-9-333
  60. 103) Moreira D de S, Magnago RF, Sakae TM, Magajewski FR. Prevalence of burnout syndrome in nursing staff in a large hospital in south of Brazil. Cad Saude Publica 2009; 25(7): 1559-1568. DOI: https://doi.org/10.1590/S0102-311X2009000700014
  61. 104) Raggio B, Malacarne P. Burnout in intensive care unit. Minerva Anestesiol 2007; 73(4): 195-200.
  62. 105) Hamid AA, Musa SA. The mediating effects of coping strategies on the relationship between secondary traumatic stress and burnout in professional caregivers in the UAE. J Ment Health 2017; 26(1): 28-35. DOI: https://doi.org/10.1080/09638237.2016.1244714
  63. 106) Pustulka-Piwnik U, Ryn ZJ, Krzywoszanski L, Stolek J. Burnout syndrome in physical therapists - demographic and organizational factors. Med Pr 2014; 65(4): 453-462. DOI: https://doi.org/10.13075/mp.5893.00038
  64. 107) Cañadas-De la Fuente GA, Vargas C, San Luis C, García I, Cañadas GR, De la Fuente EI. Risk factors and prevalence of burnout syndrome in the nursing profession. Int J Nurs Stud 2015; 52(1): 240-249. DOI: https://doi.org/10.1016/j.ijnurstu.2014.07.001
  65. 108) Navarro-González D, Ayechu-Díaz A, Huarte-Labianol. [Prevalence of burnout syndrome and its associated factors in Primary Care staff]. Semergen 2015; 41(4): 191-198. DOI: https://doi.org/10.1016/j.semerg.2014.03.008
  66. 109) Backovié DV, Zivojinovié JI, Maksimovié J, Maksimovié M. Gender differences in academic stress and burnout among medical students in final years of education. Psychiatr Danub 2012; 24(2): 175-81.
  67. 110) Raftopoulos V, Charalambous A, Talias M. The factors associated with the burnout syndrome and fatigue in Cypriot nurses: a census report. BMC Public Health 2012; 12:457. DOI: https://doi.org/10.1186/1471-2458-12-457
  68. 111) Santana Â, De Marchi D, Junior LC, Girondoli YM, Chiappeta A. Burnout syndrome, working conditions, and health: a reality among public high school teachers in Brazil. Work 2012; 41 (Suppl 1): 3709-3717. DOI: https://doi.org/10.3233/WOR-2012-0674-3709
  69. 112) Silva AT, Menezes PR. Burnout syndrome and common mental disorders among community-based health agents. Rev Saude Publica 2008; 42(5): 921-929. DOI: https://doi.org/10.1590/S0034-89102008000500019
  70. 113) WHO: Roadmap for action, 2014-2019. Integrating equity, gender, human rights and social determinants into the work of WHO.
  71. 114) "Europa 2020 strategia onnicomprensiva". http://www.prodocs.org/wp-content/uploads/2016/11/DossierParit%C3%A0GenereInUE.pdf

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